"Novel Methods and Emerging Targets in Drug Discovery & Patented Drug Development"
Announcement
The congress will be held on 13-15 December, 2018 at the BAU-Besiktas Campus, Istanbul
Congress Starting Date:
December 13, 2018
Congress Location
Istanbul - TURKEY
Organiser
Bahcesehir University
The Deadline for abstract submission: 01 October 2018
Special Issue in CHEMICAL BIOLOGY & DRUG DESIGN
CONGRESS PROGRAM ANNOUNCED!















Scientific Program
13 DECEMBER 2018 – B CONFERENCE HALL, BESIKTAS, ISTANBUL


08:00-09:30 Registration
09:30-10:00 Opening Ceremony
10:00-10:30 How many bits of information can be transferred within a protein and how fast? BURAK ERMAN


10:30-11:00 COFFEE BREAK


SESSION-I

11:00-11:30 Targeting immunosuppressive myeloid derived suppressor cells (MDSCs): A critical molecular target in metastatic process HASAN KORKAYA
11:30-11:45 The role of multidrug resistance in PARP inhibitor-resistant triple negative breast cancer cells GAMZE GÜNEY ESKİLER
11:45-12:25 METACORE/METADRUG PLATFORM SONYA NOVIKOVA


12:40 – 13:30 LUNCH


SESSION-II

13:30-13:55 Pathway based analysis of Whole Exome sequencing data reveals novel therapy candidates in Rare Diseases OSMAN UĞUR SEZERMAN
13:55-14:20 Dynamic and Static Differences between Conformations of HLA-B51 and HLA-B52: Implications for the pathogenic mechanisms of HLA-B51 in Behçet’s Disease MERT GÜR
14:20-14:45 Towards characterizing the factors tuning the specificity of biomolecular complexes EZGİ KARACA
14:45-15:00 Assessment of small molecule pKa prediction methods via the SAMPL6 blind challenge MEHTAP IŞIK
15:00-15:15 Could Allometric Scaling Rules be Valid for Proteins? YEKBUN ADIGUZEL
15:15-15:30 New Imidazo[2,1-b]Thiazol Derivatives: Synthesis, Anticancer Activity And Molecular Docking FAİKA BAŞOĞLU


15:30-16:00 COFFEE BREAK


SESSION-III

16:00-16:30 Mechanism of Action of benzazoles as topoisomerase II enzyme inhibitors ESİN AKI-YALCIN
16:30-16:55 Spatiotemporal Regulation of Chromosome Segregation in Asymmetrically Dividing Yeast Cells AYŞE KOCA ÇAYDAŞI
16:55-17:15 Development of Imidazolone Based Small Molecule As Chemotherapeutic Agent for Cell Cycle Inhibition TİMUÇİN AVŞAR
17:15-17:30 Discovery of New Sulfonyl Hydrazones with Potent Anticancer Agents in PC3 Cell Line Related to COX-2 Inhibition and Docking Studies SEVİL ŞENKARDEŞ
17:30-17:40 Determination of drug targets in cancer cells with ATR-FTIR GÜNNUR GÜLER
17:40-17:50 Plasma Membrane Changes of Human Monocytes Detected by Multicolor Flow Cytometry Coincide with FTIR Spectroscopy AYTEN NALBANT
17:50-18:00 Repair of Rat Calvarial Bone Defect by Using Exosomes of Umbilical Cord Derived Mesenchymal Stem Cells Embedded in Chitosan/Hydroxyapatite Scaffolds DİLEK BAHAR
18:00-19:00 POSTER PRESENTATIONS-I


14 DECEMBER 2018, FRIDAY - B CONFERENCE HALL, BESIKTAS, ISTANBUL


SESSION-IV

09:15-09:45 Discovery of Novel GLP-1 Modulators for The Treatmen of Diabetes MUSTAFA GÜZEL
09:45-10:15 Allosteric action in proteins TÜRKAN HALİLOĞLU
10:15-10:30 Functional Modes of GluNR12 GluNR2A2 NMDA type Receptors ŞEBNEM EŞSİZ
10:30-10:45 OmpG-16SL, an engineered porin, investigated using infrared spectroscopy FİLİZ KORKMAZ


10:45-11:15 COFFEE BREAK


SESSION-V

11:15-11:45 Fragment-Based Discovery of Chemical Probes for New Targets PAUL BRENNAN
11:45-12:10 Understanding Dynamics of G Protein-Coupled Receptor Oligomers for Development of Heterobivalent Ligands: As Novel Therapeutic Candidates for Treatment of Parkinson’s Disease ÖZGE ŞENSOY
12:10-12:20 In Silico Development of Phosphorylation-Independent Arrestins via Small Molecules MEHMET HANİFİ KURT
12:20-12:30 Synthesis of A Novel Plant Origin Radiolabeled Compound and Its in vitro Determinations on Neuroblastoma Cell Lines K. BÜŞRA KARATAY
12:30-12:40 Drug Re-Positioning Studies for Novel HIV-1 Inhibitors Using Binary QSAR Models and Target-Driven In Silico Studies BERNA DOĞAN


12:40-13:30 LUNCH


SESSION VI

13:30-14:00 Structure-Activity Relationship Analysis of Some New Benzothiazole and Benzoxazole Derivatives as hGST P1-1 Enzyme Inhibitors İSMAİL YALÇIN
14:00-14:30 Translational research for neuromuscular disorders: from genetic mutations to personalized medicine SEBAHATTİN ÇIRAK
14:30-14:55 Nanotechnology and Drug Delivery THOMAS MAVROMOUSTAKOS
14:55-15:20 Protein-Protein Interactions in Live Cells: Reinventing the Wheel ÇAĞDAŞ DEVRİM SON
15:20-15:30 Cellular Uptake of Multi Wall Carbon Nanotubes, Protein Loading and Drug Loading Qualification BİRCAN DİNÇ
15:30-15:40 Engineering Plus-end-directed Dyneins MERT GÜR


15:40-16:00 COFFEE BREAK


SESSION VII

16:00-16:30 Using simulation to improve drug design PHILIP BIGGIN
16:30-16:55 Integrated Binary QSAR Models, Text Mining and Target-driven Approaches in Virtual Screening of Small Molecules SERDAR DURDAĞI
16:55-17:10 GASPIDs (Granule Associated Serine Peptidases in Immune Defence): From Pathophysiology to novel therapeutic targets JAMSHAID AHMAD
17:10-17:25 Efficient short splice-switching morpholino antisense oligonucleotides for the treatment of Duchene Muscular Dystrophy UĞUR AKPULAT
17:25-17:40 BSA binding and in silico studies of synthesized azinane based 1,3,4-oxadiazole derivatives: Pharmacological Evaluation HIRA KHALID
17:45-18:15 SHORT TALKS-I
Biophysical Links Between Polymorphism, Stability and Peptide-Binding in the Major Histocompatibility Complex Onur Serçinoğlu
Understanding Allosteric Interaction Network within A2 AR/A2AR/Gαs-D2R/D2R-Gαi complex bound to Heterobivalent Ligand Samman Mansoor
Design, Synthesis and Cytotoxic Activity Studies of 5-Aminouracil Derived Novel Organic Molecules Ayşe Haliç
Synthesis and Characterization of Novel Branched Magnetic Chitosan Nanocomposite for Anti-Cancer Drug Loading and Release System Bilsen Tural
The identification of protein expression profile of PC3 prostate cancer and PNT1A prostate epithelial cells following anti-obesity drug Orlistat treatment regardless of AMPK signaling Elif Damla Arısan
An Investigation on the Pharmacological Components of Herbal Teas that have been used for Milk-Increasing Activities by GC / MS / MS Fidan Pesen Özdoğan
A synergistic apoptotic effect of combined treatment usnic acid with tamoxifen in breast cancer Gamze Guney Eskiler
18:15-19:15 POSTER PRESENTATIONS-II


15 DECEMBER 2018, SATURDAY - B CONFERENCE HALL, BESIKTAS, ISTANBUL


SESSION VIII

09:15-09:45 Systems level identification of drug targets overcoming resistance in breast cancer ÖZGÜR ŞAHİN
09:45-10:15 The use of systems biology in treatment of liver diseases ADİL MARDİNOĞLU
10:15-10:25 Integrative Analysis of Transcriptome Data and Genome-Scale Metabolic Networks to Identify Candidate Drug Targets and Drugs for Parkinson’s Disease ALİ KAYNAR
10:25-10:35 Anticancer Activity of Quinoline and Dihydroquinoline Derivatives MELTEM SELVİTOPU
10:35-10:45 Nanoparticles as Potential Nanocarriers for pH-responsive Investigation of the Stabilization of Topotecan Anticancer Drug BİLSEN TURAL


10:45-11:15 COFFEE BREAK


SESSION IX

11:15-11:45 Pathological Modifications and Intrinsically Disordered Proteins in Alzheimer´s Disease: Towards Antibody Design ORKIDE COSKUNER
11:45-12:15 Towards Modern Computational Drug Discovery – Integrated approaches to analyze protein drug targets from the perspectives of SNPs, allosteric regions and dynamic residue networks ÖZLEM TAŞTAN BISHOP
12:15-12:30 Searching New MAO-B Hit Inhibitors with Integrated Computational Drug Design Methods YUSUF SERHAT İŞ
12:30-12:40 Carbonic anhydrase II: The effect of single nucleotide polymorphisms on enzyme structure and function T. ALLAN SANYANGAA


12:40-13:30 LUNCH


SESSION X

13:30-14:00 Effect of Oncogenic K-Ras4B dimerization on downstream MAPK and Akt signaling ÖZLEM KESKİN
14:00-14:30 Proper interaction of canonical Wnt with its receptor complex at the cell surface is secured by the membrane lipid environment GÜNEŞ ÖZHAN
14:30-14:55 Differential requirement for centriolar satellites in cilium formation and ciliary signaling among different vertebrate cells ELİF NUR FIRAT KARALAR
14:55-15:10 Computational investigation on the escape mechanism and fitness cost of noroviruses upon mutations ABDÜLKADİR KOÇAK
15:10-15:20 Diastereoselectivity in Benzylation Reaction of 5-Methyl-Derivatives of Thiobarbituric Acids SEMİN FUNDA OĞUZ
15:20-15:30 Clay mineral particles as imaging and drug delivery agents MAİDE GÖKÇE BEKAROĞLU


15:30-16:00 COFFEE BREAK


SESSION XI

16:00-16:20 Influence of Biphalin on Human Immortalized Corneal Epithelial Cell Cultures O. MELİKE GEDAR
16:20-16:40 Evaluation of carbapenem resistance using phenotypic and genotypic techniques in Enterobacteriaceae isolates DEMET AKIN
16:40-16:55 May the Thiol-Disulfide Level be an Indicator for Diabetic Retinopathy İSA YUVACI
16:55-17:10 Oncogenic mutations on Rac1 affect global intrinsic dynamics underlying GTP and PAK1 binding SALİHA ECE ACUNER-ÖZBABACAN
17:10-17:25 Structural, Vibrational and Kinetic Analysis of a Series of Ibuprofen Derivatives by Using Ab-Initio Quantum Mechanical Calculations VEYSEL BİNBAY
17:25-17:35 In silico and in vitro Attenuation of Pseudomonas aeruginosa Quorum Sensing by Psoromic Acid BARIŞ GÖKALSIN
17:35-18:15 SHORT TALKS-II
Evaluation of SUEAH laboratory productivity commission Mehmet Özdin
Comparative Assesment of Structural and Dynamical Properties of Transforming (H-RasG12D), Non-transforming (H-RasG12P) and Wild Type HRas Protein Metehan İlter
Investigation the relationship between cholesterol metabolism and cancer through miR-33 in estrogen receptor targeting therapies in breast cancer cells Pelin Özfiliz Kılbaş
Extraction, Isolation, Characterization and Oral Bioavailability of Curcumin for the Medicinal Purposes İbrahim Demirtaş
Identification of Small Organic Molecules as Potent Catalyst Sezen Alsancak
An Investigation on Aggregation Status of Macrogol-Bound Zinc Phthalocyanine in Different Solvents Songül Şahin
Efficiency of Computationally Selected Cinchona-Derived Organocatalysts in the Reaction of Oxindole with Nitrosobenzene Yeşim Çamlısoy
Anti-proliferation Activity of Novel Heterocyclic Compounds in Tumor Cell Lines and Their Flow Cytometric Analysis Ömer Tahir Günkara
18:30-19:00 CLOSING CEREMONY AND POSTER AWARDS
 
 
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